Thursday, May 19, 2011

Phone Pulse Oximetry!

It is not surprising. This apparently works with every phone OS I believe.
http://www.engadget.com/2011/05/19/phone-oximeter-saves-lives-puts-journeys-lawyers-on-red-alert/
ulse oximetry on a cell phone



Pairing pulse oximeters with mobile phones will catapult pulse oximetry from the hospital into non-hospital settings. The inherent computing power of the mobile phone, its peripheral resources (LCD display; audio, serial and USB connectivity), battery power and everyday availability offer the opportunity to create a low-cost stand alone device that can be used by non-specialist healthcare workers and even patients at home. Real-time wireless communication of results to specialists offers another distinct advantage over traditional pulse oximeters. We are developing just such as intelligent mobile device, the Phone Oximeter.
http://www.phoneoximeter.org/the-phone-oximeter/

Wednesday, May 11, 2011

Long-term Outcome of Brain Structure in Premature Infants: Effects of Liberal vs Restricted Red Blood Cell Transfusions

Participants Magnetic resonance imaging scans for 44 of the original 100 subjects were obtained.

Intervention Liberal vs restricted transfusion.

Main Outcome Measures Intracranial volume, total brain tissue, total cerebrospinal fluid, cerebral cortex and cerebral white matter volume, subcortical nuclei volume, and cerebellum volume.

Results Intracranial volume was substantially smaller in the liberal group compared with controls. Intracranial volume in the restricted group was not different from controls. Whole-cortex volume was not different in either preterm group compared with controls. Cerebral white matter was substantially reduced in both preterm groups, more so for the liberal group. The subcortical nuclei were substantially decreased in volume, equally so for both preterm groups compared with controls. When sex effects were evaluated, the girls in the liberal group had the most significant abnormalities.

Conclusion Red blood cell transfusions affected the long-term outcome of premature infants as indicated by reduced brain volumes at 12 years of age for neonates who received transfusions using liberal guidelines.
http://archpedi.ama-assn.org/cgi/content/short/165/5/443?rss=1
Archives of Pediatrics and Adolescent Medicine

Severity of chorioamnionitis and neonatal outcome

Journal of Obstetrics and Gynaecology Research, 05/11/2011

Sato M et al. - The authors found no significant differences in stages of chorioamnionitis between infants with and without neonatal diseases except for respiratory distress syndrome. A significant inverse relationship was observed between the stage of chorioamnionitis and development of respiratory distress syndrome.
Methods

The authors reviewed the neonatal intensive care unit discharge files and placental pathology reports of 302 preterm infants.
The presence of various stages of chorioamnionitis as well as absence of an association with chorioamnionitis (non-chorioamnionitis) were compared among neonatal diseases.

Results

Preterm infants were grouped according to three stages of chorioamnionitis or the absence of an association with chorioamnionitis.
Gestational age differed significantly between these groups. Before controlling for gestational age, the chorioamnionitis stage was significantly higher among infants with chronic lung disease, retinopathy of prematurity and intraventricular hemorrhage than in infants without these diseases.
The chorioamnionitis stage was lower in infants with respiratory distress syndrome than without.
After controlling for gestational age, the stage of chorioamnionitis was significantly lower in infants with respiratory distress syndrome than in infants without respiratory distress syndrome, whereas, significant differences were not detected between the presence and absence of chronic lung disease, retinopathy of prematurity and intraventricular hemorrhage.
This is a reprint from MDlinx.com