A study published in Neonatology Vol. 98, No. 2, 2010, compared impact of 5 french catheters placed either via the nostrils or oral route on apneas of prematurity. They did not notice any difference. Most important take from this study is that, smallest NG tube may be safer for nasal placement. Since, highest airway resistance is in the nostrils, it is better to use smallest possible NG tubes.
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