Thursday, January 6, 2011

RBC Transfusions & Severe IVH!

http://onlinelibrary.wiley.com/doi/10.1111/j.1537-2995.2010.02980.x/abstract

RESULTS: Fifty-four cases were matched (1:2) with controls. No differences were found between cases and controls in initial pH, sepsis, ventilation, coagulation studies, or proportion with severe thrombocytopenia. However, during the period when the head ultrasound was normal, cases were more likely to have had a red blood cell (RBC) transfusion (p <>

CONCLUSION: These findings suggest a new hypothesis. Namely, RBC transfusions given before the development of an IVH are an independent risk factor for developing a severe IVH.

Point: One more reason to be mindful of what we do in the first week of life. This study does not mean that we have proved transfusions lead to IVH. But, it makes us pause and ponder of what we do so routinely.

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