Objective To investigate the impact of surgical closure of PDA on rScO2 and cerebral fractional tissue oxygen extraction (cFTOE), measured by near-infrared spectroscopy, and on amplitude-integrated electro-encephalography (aEEG) measured brain activity.
Design/methods In 20 preterm infants (gestational age 24.7–30.4 weeks; birth weight 630–1540 g), blood pressure, arterial saturation, rScO2, cFTOE and aEEG were monitored before, during and up to 24 h after surgery.
Conclusion Ductal ligation poses a risk for a further decrease in already compromised cerebral oxygenation in preterm infants.
My Word: this does not mean that PDA ligation has long term implications.
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