Does ECHO help decide number of Indocin doses?

Early targeted approach of using indomethacin in the first 12 hours of life if the Echocardiogram showed a duct of >2mm. Then they were randomized to echo directed indocin or standard 2 more doses of indomethacin. No differences in any complications or surgery were reported. but, the authors talk about TREND. I am not sure how trend in the absence of statistical significance has any relevance. However, they mention about higher trend of IVH in ECHO directed group than in 3 dose group. What is NOT mentioned is-the higher trend for chronic lung disease in standard 3 dose group (15% vs 6%). I believe this finding is also very important as Dr. Bancalari mentioned on Nicuniversity CME that prophylactic indocin may increase chronic lung disease. Less indocin=less CLD and more IVH?